Does Minoxidil work?


Minoxidil is one of the most effective medicine for baldness. There are many variations from different manufacturers with various additional substances to increase efficiency. 

Minoxidil is a non-hormonal medicine that stimulates new hair growth. It doesn't affect dihydrotestosterone (DHT), which is the cause of baldness. Therefore, people usually use it in conjunction with Finasteride. It usually takes four months to see the first results. Minoxidil is in the form of liquid or foam.



Does Minoxidil work?What are Minoxidil brand names?

The names differ depending on the place of sale: in the USA - Rogaine, in Europe - Regain. There are alternative products from other manufacturers. All of these medicines use one active substance - minoxidil, but the composition and concentration of excipients differ.

If you consider using Minoxidil, you probably wonder what’s the best brand to buy. The short answer is that they are all pretty much the same in terms of effectiveness. They all contain the key ingredient - 5% or 2%(for Women) of Minoxidil. Most of the big brands containing Minoxidil are the products of one company. It includes Rogaine, Kirkland and Equate. We advise you to feel free to choose any brand depending on preferences.

Here are some best brands of Minoxidil (or improved formulas of Minoxidil) we recommend you. They are on the market for many years and are proven to work for millions of people:


SPECTRAL.DNC-N hairgc1) SPECTRAL.DNC-N - solution for men and women.

Designed by DS Laboratories, Spectral.DNC-N® is the first topical hair-loss treatment to employ 5% Nanoxidil®, a powerful new alternative to Minoxidil, a compound with high efficacy, low molecular weight, and no known side effects. The compounds used in Spectral.DNC-N, have shown in various clinical studies to promote hair growth and prevent hair loss through opening ion channels within cells, suppress dihydrotestosterone (DHT), prevent perifollicular fibrosis, provide antioxidant effects, prolong the anagen phase of hair follicles, increase expression of vascular endothelial growth factor, suppress protein-kinase-C (PKC) isozymes, and block chronic inflammation.

Check Price: DS Laboratories.


Regoxidine2) REGOXIDINE - foam for men and women.

Designed by Innovus Pharmaceuticals Inc., Regoxidine® is comparable to the leading men's topical hair growth foams. Easy to use and fit into your daily routine. When used twice a day, this unscented foam targets and treats the source to improve your scalp's natural ability to grow full, dense hair.

Check Price: Buy and Save 10% Sitewide With Code REGOXIDINE10!


Rogaine

3) ROGAINEfoam or solution for men and women.

ROGAINE® is the first topical brand approved by the FDA to help regrow hair in both men and women. With more than 20 years of results and numerous clinical trials, ROGAINE® is the industry-leading, #1 dermatologist recommended brand for hair regrowth. 

Check Price on Amazon: for men (foam or solution) and women (foam or solution).



How to use Minoxidil?

Use the medicine on the bald areas of your scalp, or where the hair is not dense enough (not on the hair itself) twice a day (1 ml in the morning and evening using a pipette that comes with the kit). After you smear it, let the medicine soak for at least four hours, and then you can wash your hair.


Does Minoxidil work?Can I use Minoxidil once a day?

Yes, you can. Despite recommendations from manufacturers, one usage at night is enough if you have an initial stage of baldness (up to the third degree of baldness, according to Norwood). If there is no noticeable effect within six months, then you can increase the dosage and use it two times a day. If you use the medicine only in the evening, minoxidil will not damage hair. However, with a short haircut, a two-time application will not create any problems.


Minoxidil solution vs foam?

There is no difference in efficiency, but the foam dries faster. Medications in the form of foam are more expensive.


How long should I use Minoxidil?

You can use it all your life or while you wish to have hair on your head. Unfortunately, no medication, even minoxidil, can fixate the result (except minoxidil for beard). If you stop using it, the chances are very high that all grown hair will begin to return to its previous state or will fall out within a few months. Hair starts to fall out again and degrade due to the suspension of the growth-promoting effect that minoxidil exerts on the follicles.


Does Minoxidil work?How does Minoxidil work?

No one truly knows how minoxidil works. The mechanism of treatment is still full of mystery. There are only speculations. Scientists assume that the medication acts parabolically on follicle cells stimulating protein synthesis, which opens potassium channels of cell membranes and thus prolongs the anagen phase. Moreover, minoxidil stimulates VEGF (Vascular Endothelial Growth Factor) production. That induces angiogenesis (the growth of new vessels and capillaries in the skin), which can positively affect hair growth. In other words, minoxidil is a hair growth stimulator, probably, the best in this field among non-hormonal medications. However, it doesn't affect the source of hair loss - hair follicle susceptibility to dihydrotestosterone. Therefore, people usually use minoxidil in combination with finasteride, which reduces the concentration of dihydrotestosterone in the hair follicles.


Can Minoxidil completely restore lost hair?

In most cases, the answer is no. The full restoration of lost hair is possible only on an initial stage of baldness (1-2 degrees, according to Norwood). But if you have the third degree or higher, the chances to fully recover all lost hair are minimal.


When do the first Minoxidil results appear?

The first results usually appear after 4-6 months of use. However, some people observe the first improvements after 3 months.


Can I use Minoxidil and Finasteride together?

Yes, this is the most effective therapy. This combination of Minoxidil and Finasteride provides the highest results.


Does Minoxidil work?Are there any Minoxidil side effects?

The side effects are not common. However, in some cases, itching, dandruff, low blood pressure, face swelling, heart palpitations (if you have heart problems, consult your doctor or healthcare specialist for medical advice) may appear. In each case, the reaction is individual. Hair growth throughout the body is also possible (on the arms, legs, back) as well as enhanced facial hair growth. Some side effects usually disappear after several days of use.


Increased hair loss after using Minoxidil?

This is a normal reaction. After a few months, the hair should grow back. The mechanism is simple - the weak hair falls out, and in their place, more healthy ones grow. This phenomenon is temporary compared to the aggressive form of baldness (in this case, the hair fall does not stop).


What are the chances that Minoxidil will work?

According to studies in which 2,300 patients participated, 2% minoxidil acted as follows:

The level of impact:

  1. Nothing: no new hair was noticed.
  2. Minimal: barely noticeable growth of new hair.
  3. Small: noticeable growth of new hair.
  4. Significant: the full restoration of hair density on balding areas.

4 months (placebo)

4 months

12 months

Nothing = 68%

Nothing = 42%

Nothing = 16%

Minimum = 31%

Minimum = 32%

Minimum = 36%

Small = 9%

Small = 24%

Small = 40%

Significant = 2%

Significant = 2%

Significant = 8%


The Upjohn Company also conducted studies on the efficacy of 2% and 5% concentrations. Results after 120 weeks of use you can see below.


Noticeable/significant growth

Minimal changes

No changes

Hair loss

Unknown

5%

30%

24%

29%

6%

11%

2%

15%

23%

47%

1%

13%

Placebo

7%

22%

61%

N/A

N/A